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It was so devastating because they had found him a new heart. He literally had a heart attack right before Izzie was going to go upstairs from the prom to be with him. I still cannot believe how ridiculously simple it would have been for them to save him. I do not want to talk about Denny Duquette. This is hard to Meredith, and it was hard on all of us, too. The really terrible part of all of this is that they actually do end up getting the bomb out of the guy’s chest…only to have it blow up in the bomb squad guy’s hands, killing him instantly. The first episode ends with the paramedic succumbing to her anxiety about literally having her hands around a bomb inside of a man’s chest cavity, and as everyone throws themselves to the ground in case the bomb goes off, the camera slowly pans up to show that Meredith has taken the paramedic’s place. I only remember this entire plotline because it messed me up so bad. So, the guy with the bomb in his chest is brought in by a paramedic, and the only way she could keep the bomb from blowing up is by keeping her hand on it the whole time. Only Shonda Rhimes could make this shit up. Okay, I clumped these two together because they’re both pretty much telling the same story: that of two men who made a homemade bomb and how they got said bomb out of the literal chest of one of the men. 7) It’s the End of the World/As We Know It (2x16/17) The call that Adele, Richard’s wife with Alzheimer’s disease, had been brought to the ER coughing up blood was shocking enough, but when Bailey disregarded her own wedding in order to attempt (and, unfortunately, ultimately fail) to save Adele’s life, I’m pretty sure my own heart stopped. The fact that Richard was ready to walk Bailey down the aisle – to actually take on the role of the father figure that he had been to Bailey for so many years – was heartwarming, but on Grey’s Anatomy, you can never let your guard down. I’m still not over this episode if we’re being honest. Watching Teddy break down after she finds out her new husband, the love of her life, has died was actually heartbreaking for me. It was devastating knowing that if Cristina had been made aware of the fact that it was Henry on her table, she might have tried harder to save him, maybe done something a little extra. Teddy and Henry’s relationship to get him insurance felt very sketchy at first, but I know I soon fell in love with Henry’s charismatic, sarcastic personality. It’s one of the most heartbreaking moments on the show, especially since she had never wanted a baby in the first place but she’s so devastated by the loss. The worst part of this episode is when Cristina starts crying hysterically and screams at her colleagues to sedate her because she can’t stand the way that she’s feeling. She hadn’t wanted the hospital to know, but they find out when they have to operate on her. In case, you can’t remember that far back, this was the episode during which Cristina collapses in the OR because her pregnancy turned out to be ectopic. It really reminded me of the time that I had to watch the film Dead Man Walking, starring Sean Penn, in my high school government class and I couldn’t help but to sympathize (until we found out he really killed that girl, though. Meredith feels sympathy for William because he confides in her that he’s afraid to die. I know it was a really controversial episode, but when Meredith sat in on the execution of William Dunn, a death row inmate, despite Derek’s anger with her for doing so. It’s so sad watching all of the doctors reacting to the thought of losing Callie, and the fact that they used all of the heart-wrenching music we have grown to hate because it signals the death of a character we love. One of the most heartbreaking lines of the season, maybe even the series, is uttered by Arizona after they arrive at Seattle Grace: “I asked her to marry me and a truck came out of nowhere.” They end up saving both Callie and the baby, but the most insufferable part of the whole episode is not knowing whether or not they’ll make it.